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Endo-Treat

Helps alleviate Endometriosis and PMS symptoms and bleeding
Endometriosis is a debilitating disease, defined by the presence of functioning endometrium-like tissue outside the uterus. It is the most prevalent benign gynaecological disease worldwide, estimated to affect 10% of women in reproductive ages. Symptoms include chronic pelvic pain, fatigue, dysmenorrhoea, dysuria, dyspareunia, dyschezia and infertility. These can greatly affect the physical, mental, sexual and social wellbeing of patients and cause high societal costs. Costs are further incurred by the considerable diagnostic delay of endometriosis, which varies throughout studies, but can take up to 10 years from the onset of symptoms. 
Although the exact pathogenesis is yet unknown, retrograde menstruation is currently the most accepted theory for the cause of endometriosis.
Each package contains: 60 herbal capsules.
Recommended use: One capsule, twice a day.

Endo-Treat Benefits

  • Acts as a local pain killer by releasing pain mediators such as prostaglandin, interleukin and histamine or centrally through CNS via sensory nerve impulses.

  • Effective at breaking down unwanted tissues cells and allowing our bodies to function more normally.

  • Is a beneficial product that targets reproductive health issues at the source and aids in bettering the inner and outer health of women suffering with endometriosis.

  • Serrapeptase has an immense range of abilities, including the ability to dissolve dead tissue, blood clots, scars, and fibrous cysts located in the breasts and uterus.

  • A good therapeutic candidate for inflammatory, immune, and metabolic diseases.

  • A good candidate for the regulation of cell growth, hormone release, immunological response and reproduction.

  • Endo-Treat is a key anti-inflammatory nutrient  because of the content of zinc that is commonly deficient in women with endometriosis. Zinc repairs intestinal permeability (thereby improving autoimmunity) and reduces prostaglandins and pain.

Description

Endometriosis is a debilitating disease, defined by the presence of functioning endometrium-like tissue outside the uterus. It is the most prevalent benign gynaecological disease worldwide, estimated to affect 10% of women in reproductive ages. Symptoms include chronic pelvic pain, fatigue, dysmenorrhoea, dysuria, dyspareunia, dyschezia and infertility. These can greatly affect the physical, mental, sexual and social wellbeing of patients and cause high societal costs. Costs are further incurred by the considerable diagnostic delay of endometriosis, which varies throughout studies, but can take up to 10 years from the onset of symptoms.

Although the exact pathogenesis is yet unknown, retrograde menstruation is currently the most accepted theory for the cause of endometriosis. Various genetic, hormonal, environmental (including organochlorine pesticides, which can be ingested through fish, fatty foods and dairy products) and immunological factors are thought to influence the development of this oestrogendependent inflammatory disease.

(information source​)

Endometriosis is best defined as an inflammatory disease in which bits of tissue that are similar to uterine lining grows throughout the pelvis on structures such as ovaries. It causes pain (sometimes severe), scarring, and infertility. Risk factors include genetics and exposure to toxins such as pesticides and dioxins.

The microbiome (good bacteria) also plays a role. For example, women with endometriosis have a high level of gram-negative bacteria and the bacterial toxin LPS (lipopolysaccharide) in their pelvis, which can actively promote endometriosis and may be an initiating cause of endometriosis. Endometriosis is common and often starts young (although it can take ten years to diagnose). One study found that two-thirds of teens reporting chronic pelvic pain will eventually go on to be diagnosed with endometriosis. 

(information source​)

Endo-Treat Ingredients

Henna extract (Lawsonia Inermis)

Lawsonia inermis Linn (Family: Lythraceae) is a plant often known as henna, predominant in tropical and subtropical regions and has been extensively investigated and used worldwide in traditional medicine and as cosmetic. it is used traditionally as abortifacients to treat gonorrhea, intestinal amebiasis, headache, sore throat (decoction), as a blood tonic, hair tonic and treats dandruff and scalp disorders for Jaundice, skin disorders, fever, malaria, conjunctivitis, pimples, and scabies. (From the article THE ANALGESIC AND ANTI-INFLAMMATORY EFFECT OF LAWSONE ISOLATED FROM LAWSONIA INERMIS published in ScienceRise: Pharmaceutical Science)

 

Pain is a major symptom of many medical conditions and the most indicator of many medical cases, the pain either locally by release of pain mediators such as prostaglandin, interleukin and histamine or centrally through CNS via sensory nerve impulses. Therefore, ethanolic leaves extract of L. inermis clarified both central and peripheral analgesic activity, similar to ketoprofen by increase reaction time via thermal stimulus and decrease abdominal constriction via chemical stimulus (acetic acid) by inhibition of the local endogenous pain mediator such as prostaglandin and bradykinin. Lawsonia inermis L. contain many phytochemical compounds such as tannin, alkaloid, flavonoids and steroids which have been possess potent analgesic activity.

 

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Papaya extract (Serrapeptase)

: Serrapeptase is a naturally occurring proteolytic enzyme, isolated from the silkworm and other natural resources. This proteolytic enzyme is able to digest certain types of protein by attacking only dead tissues. This would include adhesions, dead cysts and scarring. Studies suggest that this enzyme in the body produces anti-inflammatory mediators that reduce swelling, redness, and pain. Endometriosis has some key symptoms including scarring, cysts, inflammation, pain and adhesions. Serrapeptase is effective at breaking down these unwanted tissues cells and allowing our bodies to function more normally. Serrapeptase also reduces inflammation and pain by blocking pain inducing amines. (information source​)

 

Endometriosis at its worst is correlated with fertility issues, immense pain during menstrual periods, as organs becoming stuck to one another, as the symptoms worsen life becomes more difficult, many have found Serrapeptase for endometriosis a success. Serrapeptase when used for endometriosis is a beneficial enzyme that targets reproductive health issues at the source and aids in bettering the inner and outer health of women suffering with endometriosis. Serrapeptase has an immense range of abilities, including the ability to dissolve dead tissue, blood clots, scars, and fibrous cysts located in the breasts and uterus.

(information source​​)

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Sweet wormwood extract (Artemisia Judaica)

Endometrial carcinoma is the most common gynecological cancer in the United States and fourth most common cancer among women, after breast, lung, and colon cancer with 47,130 cases and 8,010 deaths reported in 2012. There are two distinct types of endometrial cancers based on histological and molecular characteristics. Type I tumors, referred to as the endometrioid type, are generally well-differentiated adenocarcinomas with or without squamous differentiation, whereas Type II, the nonendometrioid type, are uterine papillary serous and clear-cell carcinomas. Type I tumors comprise approximately 80-90% of all endometrial cancers. Naturally occurring plant compounds represent a largely untapped source of potential chemotherapeutic molecules to control different types of cancers with very minimal side effects. One such phytochemical is artemisinin, which is a sequiterpene lactone that was isolated from the aerial portions of the Artemisia annua plant (more commonly known as qinghaosu or sweet wormwood). For over 2000 years, Chinese traditional medicine practitioners have utilized this herb to treat a variety of illnesses, such as intestinal parasitic infections, hemorrhoids, and fever. Recent studies have demonstrated that artemisinin and its derivatives exhibit potent anticancer effects in a various human cancer cell model systems such as colon, melanoma, breast, ovarian, prostate, central nervous system, leukemic, and renal cancer cells. (information source​)

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Purslane (Portulacca)

Portulaca oleracea, known as Purslane, is an annual growing herb with wide distribution around the world and traditionally used to manage several diseases. Different therapeutic properties as an anti-fever agent as well as anti-inflammatory and analgesic effects have been attributed to P. oleracea. (information source​)

Purslane (Portulaca oleracea L.), believed to be the earliest vegetable consumed by human has been a part of traditional culinary and folk medicine system since long back. It is a rich source of vitamins, flavonoids, alkaloids, polysaccharides, omega-3 fatty acids (Especially alpha-linolenic and gamma linolenic acids), terpenoids, sterols, proteins and minerals and has also been reported as the super food for the future. Owing to its diverse phytoconstituents, Purslane has been reported to possess potent pharmacological actions such as hepato-protective, neuroprotective, antiinflammatory, antimicrobial, antidiabetic, antioxidant, anticancer, antihypertensive actions. (From the article " Purslane (Portulaca oleracea L.): An underutilized wonder plant with potential pharmacological value", The Pharma Innovation Journal).

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Juniperi

It was found that Juniperi had strong anti- inflammatory, immune modulatory, and wound healing activities. More interestingly, Juniperi impacted critical genes and pathways that are associated with metabolism, inflammation, and cancer biology. Findings from this study suggest that Juniperi may be a good therapeutic candidate for inflammatory, immune, and metabolic diseases.

(information source​)

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Zinc

Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. Only recently, attention has been drawn to the potential role of zinc in polycystic ovary syndrome (PCOS), dysmenorrhea, or endometriosis. In primary dysmenorrhea, zinc supplementation before and during each menstrual cycle seems to be an important factor reducing the intensity of menstrual pain. (information source​)

 

The results of a study of possible involvement of zinc in the complex pathogenic process behind the onset and perpetuation of endometriotic lesions showed that serum zinc levels in women with endometriosis are decreased and this seems to actually confirm that this micro-element can possibly affect the multifactorial pathogenesis of the disease. As a matter of fact, zinc interferes with many biological processes, among which inflammation and immunity, which seem to be the base of the development of the lesions.

(information source​)

 

Zinc is a key anti-inflammatory nutrient that is commonly deficient in women with endometriosis. Zinc repairs intestinal permeability (thereby improving autoimmunity) and reduces prostaglandins and pain. (information source​)

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